◉Swallow the tablets/capsule whole, do not crush or chew

Follow your doctor’s instructions for adjusting your dose.

Composition of Drug
◉This drug contain Cilnidipine 10mg + chlorthalidone 12.5 mg.
How does the Drug work
◉Cilnidipine and chlorthalidone are two different medications commonly prescribed for hypertension (high blood pressure). When combined, they can work synergistically to effectively control blood pressure in patients who do not respond well to single-drug therapy.

◉ Cilnidipine:Cilnidipine is a calcium channel blocker (CCB). It works by blocking calcium channels in the smooth muscle cells of blood vessels. These channels are responsible for allowing calcium to enter the cells, leading to vasoconstriction (narrowing of blood vessels). By inhibiting calcium influx, cilnidipine causes vasodilation (relaxation of blood vessels), reducing peripheral resistance. As a result, the heart doesn’t have to work as hard to pump blood, and blood pressure decreases.

◉ Chlorthalidone:Chlorthalidone belongs to the thiazide diuretic class of medications. It acts on the kidneys, where it inhibits sodium reabsorption. When sodium is not reabsorbed properly, it is excreted in the urine along with water. As a consequence, the overall volume of blood decreases, and the heart’s workload is further reduced. Lower blood volume and decreased fluid retention also contribute to lower blood pressure.

◉ Combining Cilnidipine 10mg with chlorthalidone 12.5mg takes advantage of their different mechanisms of action. The calcium channel blockade of cilnidipine reduces vascular resistance, while chlorthalidone’s diuretic effect helps lower blood volume. Together, this combination can effectively lower blood pressure in hypertensive patients, especially those who may not respond adequately to either medication alone.

◉ It is essential to note that these medications should only be used under the guidance and prescription of a qualified healthcare professional. They will monitor your blood pressure and make any necessary adjustments to the dosage or combination of drugs to ensure the best possible outcome and minimize any potential side effects.