◉Swallow the tablets/capsule whole, do not crush or chew
Follow your doctor’s instructions for adjusting your dose.
Composition of Drug
◉This drug contain Telmisartan 40mg+ cilnidipine 10mg +chlorthalidone 12.5 mg.
How does the Drug work
◉Telmisartan, Cilnidipine, and Chlorthalidone are three different medications often used in combination to treat hypertension (high blood pressure). Let’s look at each medication’s mechanism of action and how they work together:
◉ Telmisartan:Telmisartan belongs to a class of medications known as angiotensin II receptor blockers (ARBs). It works by blocking the action of angiotensin II, a hormone that causes blood vessels to constrict. By blocking angiotensin II, Telmisartan helps to relax and widen blood vessels, reducing blood pressure and improving blood flow.
◉ Cilnidipine: Cilnidipine is a calcium channel blocker (CCB) that mainly blocks both L-type and N-type calcium channels in the blood vessels. By doing so, it reduces the entry of calcium into the smooth muscle cells of blood vessels, leading to relaxation and dilation of the blood vessels. This action helps to lower blood pressure.
◉ Chlorthalidone:Chlorthalidone is a thiazide-like diuretic, commonly referred to as a water pill. It works in the kidneys by increasing the excretion of sodium and water from the body, which decreases the volume of fluid in the blood vessels. As a result, there is less fluid to pump through the blood vessels, and the heart’s workload is reduced, leading to lower blood pressure.
◉ When these three medications are combined, they work synergistically to lower blood pressure through different mechanisms:,,Telmisartan blocks the effect of angiotensin II, reducing vasoconstriction and promoting vasodilation
Cilnidipine relaxes and widens the blood vessels by blocking calcium channels
Chlorthalidone helps to reduce the volume of fluid in the blood vessels, further decreasing blood pressure
The combination of these three drugs allows for a more effective reduction in blood pressure compared to using each medication alone. However, it’s essential to use this combination under the guidance and supervision of a healthcare professional, as it may not be suitable for everyone, and regular monitoring is necessary to ensure safety and efficacy. Additionally, the dosages may vary depending on the individual’s condition and response to treatment.





