◉Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it.
Composition of Drug
◉This is drug contain Mycophenolic acid (gr) 360 mg.
How does the Drug work
◉Mycophenolic acid is works by decreasing the body’s immune system and prevents rejection of the organ transplant.Mycophenolate mofetil, often abbreviated as MMF or mycophenolate (GR) in this context, is an immunosuppressant medication that is used to prevent the rejection of transplanted organs (such as kidney, heart, liver, and others) and to treat certain autoimmune conditions. The active form of mycophenolate mofetil is mycophenolic acid (MPA)
Inhibition of Inosine Monophosphate Dehydrogenase (IMPDH): Mycophenolate works by inhibiting an enzyme called inosine monophosphate dehydrogenase (IMPDH), which is critical for the de novo synthesis of guanosine nucleotides (building blocks of DNA and RNA) in rapidly dividing cells, including activated lymphocytes (immune cells). By interfering with this process, mycophenolate prevents the proliferation of immune cells, particularly T and B lymphocytes, which play a key role in organ rejection and autoimmune diseases
Reduced Lymphocyte Proliferation: As a result of IMPDH inhibition, mycophenolate reduces the production of new DNA in lymphocytes, limiting their ability to divide and multiply. This leads to a decrease in the overall immune response, which is beneficial in transplant patients to prevent the immune system from attacking the transplanted organ and in autoimmune conditions where the immune system is attacking the body’s own tissues
Selective Action on Immune Cells: Mycophenolate’s mechanism of action is relatively selective for immune cells because they rely more on de novo guanosine nucleotide synthesis compared to other cells in the body. This selective action helps minimize some of the side effects seen with other more broadly acting immunosuppressive drugs.$$It’s important to note that mycophenolate is typically used in combination with other immunosuppressive medications to achieve the desired level of immune suppression while minimizing side effects and ensuring the success of organ transplantation or autoimmune disease management.
