◉Swallow the tablets/capsule whole, do not crush or chew
Follow your doctor’s instructions for adjusting your dose.
Composition of Drug
◉This drug contain Metoprolol (er) 50 mg+cilnidipine 10 mg.
How does the Drug work
◉Metoprolol and cilnidipine are two different medications used to treat various cardiovascular conditions. Let’s take a look at each one and then discuss how they work together when prescribed in combination
Metoprolol (ER) 50 mg: Metoprolol is a beta-blocker, specifically a selective beta-1 blocker. It works by blocking the action of adrenaline and noradrenaline on the beta-1 receptors in the heart and blood vessels. By doing so, metoprolol reduces the heart rate and the force of contraction of the heart muscle, leading to a decrease in blood pressure. It also helps in reducing the workload on the heart, making it an effective treatment for hypertension (high blood pressure), angina (chest pain), and certain heart rhythm disorders.
◉ Cilnidipine 10 mg: Cilnidipine is a calcium channel blocker (CCB) that acts on L-type calcium channels found in the smooth muscle cells of blood vessels. Unlike traditional CCBs, cilnidipine has dual-blocking action, targeting both N-type and L-type calcium channels. By blocking these channels, cilnidipine relaxes and dilates the blood vessels, reducing peripheral vascular resistance, and subsequently lowering blood pressure. Its action is particularly beneficial in managing hypertension.
◉ Combining Metoprolol (ER) and Cilnidipine 10 mg: When prescribed together, Metoprolol (ER) and Cilnidipine 10 mg can complement each other’s actions to provide more effective blood pressure control. The combination of a beta-blocker like metoprolol and a calcium channel blocker like cilnidipine allows for a broader impact on blood pressure regulation. They both target different pathways involved in blood pressure regulation, leading to enhanced efficacy and potentially minimizing side effects that may occur with higher doses of a single medication.
◉ It’s essential to follow your doctor’s advice and take the medications as prescribed. If you have any concerns or experience any side effects, be sure to discuss them with your healthcare provider. As with any prescription medication, individual responses may vary, so it’s crucial to monitor your blood pressure and report any changes to your doctor.
